【摘要】 目的:探讨血小板的活化释放功能和抗凝血系统功能,在观察重症急性胰腺炎病程发展变化的临床价值。方法:测定血浆β-血小板球蛋白、血小板第4因子、血栓素B₂、血小板颗粒膜蛋白、血浆5-羟色胺、抗凝血酶-Ⅲ抗原及活性、蛋白C抗原及活性等指标。结果:急性水肿型胰腺炎各项指标均与对照组间无显著性差异（P>0.05）,急性出血坏死型胰腺炎血小板各项指标均高于对照组（P<0.01）,抗凝血系统各项指标均低于对照组（P<0.01）。结论:急性出血坏死型胰腺炎血小板功能被激活,抗凝血系统水平和活性低下,测定这些指标对了解病程发展和预防并发症具有一定意义。更多还原

【Abstract】 To investigate the clinical value of changes of platelet and anticoagulation function in patients with acute pancreatitis. Methods:β-TG,PF4 .TXB2 ,GMP-140,antithrombin-III,and protein C were measured in all patients. Results: There was no significant difference in all parameters between acute edema pancreatitis group and normal group(P>0.05). Compared with the control group, parameters of platelet significantly increased in acute necrosis pancreatitis group(P< 0.01), and parameters of anticoagulation significantly decreased (P < 0.01). Conclusion: The platelet system was activated and the level of anticoagulation system decreased in acute necrosis pancreatitis. Parameters are important in understanding and preventing this disease.更多还原