【摘要】 目的 :研究绿茶儿茶素 (GTC)与抗癌药阿霉素 (ADM)、5 -氟尿嘧啶 (5 -Fu)和阿糖胞苷 (AraC)联合应用对人肝癌细胞体外生长的抑制作用。方法 :应用MTT法检测GTC先于抗癌药、抗癌药作用后或与抗癌药同时作用 ,对BEL -7402和SMMC -7721人肝癌细胞的生长抑制作用。结果 :GTC与抗癌药有相加性抑瘤效应。结论 :GTC很可能具有临床应用前景更多还原

【Abstract】 Objective: To examine the effects of green tea catechins (GTC) with antitumor drugs such as adriamycin(ADM), 5-fluorouracil(5-Fu) and cytarabine(Arac) on the growth inhibition of BEL-7402 and SMMC-7721 human hepatocarcinoma cell lines. Methods: MTT colorimetric assay was used to examine the cell proliferation. Results: The results showed that combination of GTC and antitumor drugs potentiated the inhibitive effects on the hepatocarcinoma cells. Conclusion: It is suggested that GTC maybe a promising cancerous chemopreventive agent and chemotherapetic adjuvant.更多还原