【摘要】 目的 :观察干扰素γ治疗烧伤增生性瘢痕后瘢痕色度值的变化。方法 :选择烧伤后瘢痕患者38例。瘢痕内注射重组干扰素γ100万国际单位 ,每周一次 ,连续注射4次。选同体瘢痕用注射灭菌注射用水治疗作对照 ,于治疗前和治疗后4周和8周 ,用光电检测技术测量瘢痕的色度值 ,并观察患者的自觉症状 (痒、胀、痛 )、瘢痕的充血、颜色等变化。结果 :用干扰素γ治疗增生性瘢痕后4周、8周 ,瘢痕的色调、饱和度值均明显低于对照组 (P<0.01) ,患者的自觉症状 (痒、胀、痛 )减轻、瘢痕的充血减轻、颜色变浅。结论 :用干扰素γ治疗增生性瘢痕后瘢痕的色度值明显降低 ,干扰素γ是治疗增生性瘢痕疗效明显的药物之一。更多还原

【Abstract】 Objective: To observe changes of chroma value in burned hypertrophic scar tissue after using interferon-γ treatment. Methods: Chroma values of hypertrophic scars were determined by photo-electricity test technology, changes of hyperaemia of scar tissue and scar colour as well as other physiological symptoms in 38 burned patients were observed before using interferon-γ treatment, and during weeks 4 and 8 after using interferon-γ treatment once a week(total 4 weeks).The control group received sterile water injections to the scar tissue. Results: The values of hue and saturation of hypertrophic scars from weeks 4 and 8 after using interferon-γ treatment were lower than those in the control group (P<0.01). Physiological symptoms in patients were relieved, hyperaemia of scar tissue and scar colour all improved significantly. Conclusion: Chroma values of hypertrophic scar tissue decreased significantly after using interferon-γ treatment. The use of interferon-γ has proven effective for treatment of hypertrophic scars.更多还原