【摘要】 介绍了以 1 ,2 -环己二胺为原料制备 1 ,2 -环己二胺四乙酸的合成方法 ,通过正交设计实验考查了DCTA合成中原料摩尔比、反应时间、反应温度等因素对合成反应的影响 ,并获得了最优化的反应条件 :n( 1 ,2 -环己二胺 ) /n(氯乙酸 ) =1∶6;反应温度为 5 0℃ ;反应时间为 7h。该工艺具有成本低、反应条件温和等特点 ,也为 1 ,2 -环己二胺的深加工提供了新的方法。同时将该法生产的DCTA与进口同类产品进行了比较 ,产品质量指标达到或超过进口试剂的质量标准。又通过应用试验对DCTA与EDTA的化学性质进行了对比 ,结果表明 ,采用此工艺生产的DCTA产品质量可靠、稳定性好、性能优越 ,可替代EDTA应用于化学工业中更多还原

【Abstract】 The preparation methods of 1,2-cyclohexylenedinitrilotetraacetic acid (DCTA) are discussed in detail when cyclohexadiamine is used as the material, and the effect of reaction temperature,reaction time,the molar ratio of the material on the yield is investigated by the orthogonal design, the optimum reaction conditions are obtained: n (1,2 cyclohexanediamine): n (chloro acetic acid)=1∶6; The reaction temperature is 50 ℃, the reaction time is 7 h. Thus this process is with the low costs,the mild reaction conditions, it provides a new method for the deep processing of 1,2-cyclohexanediamine . In the meanwhile, this product has been compared to the same kind product from foreign country, the performance figures of this product have reached or exceeded the quality standard of the input reagent. And the chemical property of DCTA and EDTA are compared by the application test, and the result shows that the quality of DCTA product is reliable, stabile , the performance is fine. Thus it can be used as substitution of EDTA in the chemical industry.更多还原