【摘要】 目的　探讨食管癌术后综合治疗疗效以及影响预后的因素。方法　 2 80例食管癌 ,随机分为单纯手术组 10 0例和综合组 (即术后化疗加放疗组 ) 180例。结果　根治切除术后 5年生存率 :单纯手术组 18 6 % (8/4 3) ,术后综合组 35 % (35 /10 0 ) ,P <0 0 5 ;而姑息切除术后 5年生存率 :单纯手术组为 0 ,综合组为 2 0 % (16 /80 ) ,P <0 0 0 1。综合组局部复发率为 12 % (12 /10 0 )明显低于对照组的 2 7 9% (12 /4 3) ,P <0 0 5。结论　术后辅以化疗和放疗 ,可以提高病人的 5年生存率 ,而且可以减少术后复发和转移的发生。更多还原

【Abstract】 Objective To study the clinical results of post-operative combined therapy of esophageal carcinoma and the factors which affect prognosis.Methods From February 1990 to April 1994 our hospital treated 280 cases of esophageal carcinoma. The patients were divided randomly into two groups, one(100 cases) receiving simple operative treatment(operation group) and the other (180 cases) receiving post-operative combined therapy (radio-chemotherapy).Results The post-operative survival rate for five years after being cured through radicaling simple operative group was 18.6%(8/43), combined therapy group was 35%(35/100),P<0.05. However the post-operative survival rate for five years after being cured through palliative simple operative group was zero, combined therapy group was 20%(16/80),P<0.001. The partial attack rate of combined therapy group was 12%(12/100) obviously lower than the control group 27.9%(12/43), P<0.05.Conclusion The post-operative auxiliary radio-chemotherapy can enhance patients’ five-year survival rate. Furthermore chances of recurrence and metasis after operation can be reduced.更多还原