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前β1-HDL与细胞HDL受体结合活性的研究

Study on the Activity of Pre-β1HDL Binding to HDL Receptors on Different Cell Types

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【作者】 吴新伟傅明德徐燕华

【Author】 WU Xin wei,FU Ming de *,XU Yan\|hua (Apolipoprotein Research Laboratory,West China University of Medical Sciences,Chengdu 610041,China)

【机构】 华西医科大学载脂蛋白研究室!成都610041

【Abstract】 The activities of pre\|β 1HDL and apoE\|deficient HDL 3 binding to HDL receptors on human SMC,HepG2 and macrophage were detected using enzyme linked immune receptor assay(ELIRA).The results showed the value of K d of pre\|β 1 HDL binding to HDL receptor was significantly lower than that of apoE\|deficient HDL 3( P <0.05),but B max showed no difference.The results suggested that the affinity of pre\|β 1 HDL to HDL receptor was significantly higher than that of apoE\|deficient HDL 3.

【关键词】 pre\|β 1 HDLapoE\|deficient HDL\-3ELIRA
【Key words】 pre\|β 1 HDLapoE\|deficient HDL\-3ELIRA
  • 【文献出处】 中国生物化学与分子生物学报 ,Chinese Journal of Biochemistry and Molecular Biology , 编辑部邮箱 ,2001年01期
  • 【分类号】Q26
  • 【被引频次】1
  • 【下载频次】36
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