Objective To study the effect of insulin treatment on the function of islet in type 2 diabetes mellitus. Methods 100 type 2 diabetic patients with a history of more than 10 years and with high blood glucose were randomly divided into Group A and Group B. In Group A, the patients were given regular oral hypoglycemic. In Group B, the patients were given insulin intensive treatment. A measurement of C-peptide was carried out before and after the treatment.\ Results In Group B ,the C-peptide level was ...