【摘要】 关于肿瘤细胞多药抗性机制的研究是肿瘤研究的焦点之一，而糖蛋白Ｐ的发现使细胞多药抗性研究取得了重大进展，糖蛋白Ｐ是耐药基因ｍｄｒ的产物，起到药物外排泵的作用，把药物主动排出产生抗药性的肿瘤细胞外．而且糖蛋白Ｐ的表达具有组织特异性．在正常组织中，作为一个广谱特异性转运分子参与机体代谢．这些研究无疑会推进癌肿基础研究的进展．更多还原

【Abstract】 The study on multi - medicinal resistance is one of key problems on tumor researching, and the study has made a great progress as the discovery of glycoprotein p. Glycoprotein p is the product of medicinal resistant gene md, it pumps medicine out of tumor cell. The present of Glycoprotein p has tissue specificity. These studies will bring prefound affaction on tumor cell research.更多还原