【摘要】 目的　判断切除卵巢的绝经后骨质疏松模型成功与否 ,一般用 DXA测量的 BMD指标判断 ,难免有误。方法　本文根据骨承受的最大外力始终与体重成正比的原则 ,30只大鼠造模试验得到 BMC、BMD与体重的相关系数。结果　BMC、BMD与体重的相关系数分别为 0 .915和 - 0 .2 89,用 BMD分析这批动物造模未能成功 ,而以体重标准化 BMC分析则造模成功。结论　 BMC在此应用中优于 BMD。更多还原

【Abstract】 Objective DXA measured bone mineral density.(BMD) is usually used to determine whether the model of ovariectomy induced postmenopausal osteoporosis is a success,but it is hard to avoid mistakes in using this method.Methods This study was made to compare the bone mineral content (BMC)with BMD in this aspect.In the light of the principle that the biggest stress bone borne is in direct proportion to the body mass,we put 30 female SD rats in a moulding test.Results The correlation coefficients between the BMC,BMD and the weight were found to be 0.915 and 0.289 respectively.This animal model is not a success as detarmined by BMD analysis,but it is a success as evaluated by body mass standardized bone mass analysis.Conclusion Suggesting that BMC is superior to BMD in this aspect.更多还原