【摘要】 合成的 5种医用蓖麻油基聚氨酯灌封胶经γ -射线消毒处理后 ,用高压液相色谱 (HPLC)测定了灌封胶中的 4,4′-二胺基二苯基甲烷 (MDA)含量 ,并定量探讨了γ -射线辐照对灌封胶力学性能的影响。实验结果证明 ,γ-射线的辐照剂量越大 ,灌封胶中产生MDA量就越多。经 2 5kGy的γ -射线消毒后 ,5种灌封胶中MDA累积含量分别为 10 33、10 37、10 5 2、10 5 9与 10 91μg/g ,但这样的MDA量远不致危害人体健康。γ -射线辐照后 ,灌封胶的力学性能 (拉伸强度、撕裂强度与硬度 )均有所增高 ,此乃是辐照使灌封胶结构发生交联所致更多还原

【Abstract】 After γ-ray sterilization, the amounts of 4,4′-methylenedianiline (MDA) in the five kinds of synthesized medical castor oil polyurethane potting materials were detected by HPLC. The influences of γ-ray irradiation on the mechanical performance of the potting materials were also discussed quantitatively.The experimental results showes that the amounts of produced MDA increases with γ-ray irradiation dosagee. After 25 kGy γ-ray sterilization, the accumulated amounts of MDA in the five kinds of potting materials were 10.33, 10.37, 10.52, 10.59, 10.91 ?μg/g respectively. Those amounts are below the level of harmamount to human body. At the same time, the mechanical properties of the potting materials such as tensile strength, tear strength and hardness are improved because cross linking happens under irradiation.更多还原