Objective To observe the effectiveness and safety of chemotherapy of the late stage of NSCLC with combined regime of NVB.Method Forty-six patients with NSCLC with a stage of Ⅲ~Ⅳ confirmed with pathology were treated with the combined regime of NVB.The physical examination,laboratory examination and radiography were performed before and 2~3 cycles after the chemotherapy.The effectiveness and toxicity were evaluated after 2~3 cycles of the chemotherapy.Result The rate of effectiveness of the regime was 4...