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利用超临界CO2制备α-细辛醚及布洛芬微细颗粒
Study on the process of formation of fine α-asarone and ibuprofen particle by rapid expansion of supercritical solution
【摘要】 用超临界CO2 法制备了药物α 细辛醚和布洛芬的微细颗粒 ,考察了膨胀压力、膨胀前温度、沉析室温度、喷嘴直径等因素对颗粒平均直径的影响 .对制备的微粒分别用XRD ,SEM进行了表征
【Abstract】 Formation of fineα-asarone and ibuprofen particle by rapid expansion of supercritical solution , effects of technique condition such as expansion pressure,preexpansion temperature,precipitation temperature,nozzle diameter to fine and uniform particles were investigated,respectively. The characteristics of fine ibuprofen particles was analysed by XRD,SEM.
【关键词】 超临界CO2;
α-细辛醚;
布洛芬;
微细颗粒;
【Key words】 supercritical CO 2; α-asarone; ibuprofen; fine particles;
【Key words】 supercritical CO 2; α-asarone; ibuprofen; fine particles;
- 【文献出处】 宁夏大学学报(自然科学版) ,Journal of Ningxia University(Natural Science Edition) , 编辑部邮箱 ,2001年02期
- 【分类号】TQ460
- 【被引频次】14
- 【下载频次】89