【摘要】 采用放射免疫方法测定了 9名武术散手运动员大运动量训练期安静时内皮素(endothelin ,ET)、降钙素基因相关肽 (calcitoningenerelatedpeptide ,CGRP)和心钠素 (atrialnatyiureticpeptide ,ANP)等心血管激素 .随着大运动量训练的深入 ,散手运动员血浆ET水平呈逐渐升高趋势 ,直至后两次取样点时出现显著差异 .剧烈运动时 ,血浆儿茶酚胺及血管紧张素浓度增加 ,刺激ET分泌增加 .另外 ,骨骼肌和心肌缺血、缺氧或损伤 ,也可导致ET的分泌增加 .训练初期散手运动员血浆CGRP水平逐渐下降 ,但无显著差异 ,随着训练时间的延长该激素水平下降明显 ,表明与短时间极限运动的作用不同 ,长期训练可使机体CGRP分泌减少 .ET/CGRP比值的变化随着训练时间的推移 ,呈逐渐上升趋势 .ANP水平在训练初期显著提高 ,之后的训练中始终高于训练前 ,到最后测试点时与其前两个点比较也有显著差异 ,说明比赛前大强度训练对散手运动员心脏激素的作用很大 .ET与CGRP之间的变化具有明显的负相关 ,CGRP与ANP之间具有非常显著的负相关 ,ET与ANP之间有非常显著的正相关 .ET、CGRP和ANP水平变化与血液浓缩无关 .更多还原

【Abstract】 This work had used radioimmunological method to determine 9 male Wushu free sparring athletes((24.30±4.20)?year,(170.30±3.8)?cm,(68.30±4.20)?kg) peaceful level of cardiovascular hormones,include endothelin (ET),calcitonin gene related peptide(CGRP) and atrial natyiuretic peptide(ANP).During and after 3 months high intensity training,The level of ET increased gradually and at last two points of measurement hormone concentration significantly increased.The result suggests that increased plasma catecholamine and hypertensin secretion and/or anoxic and damage of skelecton muscle and cardiac muscle would have caused enhancing ET level;At the begining of high intensity training CGRP level decreased gradually and along with the training the CGRP level significantly decreased.The change suggests that the effect of long term training was different from short term exercise.Along with the intensity training ET/CGRP ratio was increased.It clues on dislocation the secretion of ET and CGRP.The level of ANP increased gradually and at last two points of measurement it significantly higher than pre training.This result suggests that the effect of high intensity training on ANP was significant; Another result showed that there was a significant negative correlation between ET and CGRP,a significant negative correlation between CGRP and ANP,a significant negative correlation between ET and ANP; This work suggests that the changes of hormone were not related to blood concentration.更多还原