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低密度脂蛋白结构研究进展
ADVANCES IN STUDIES ON STRUCTURE OF LOW DENSITY LIPOPROTEINS
【摘要】 摘要:本文对低密度脂蛋白(LDL)的形成、结构做了简单概述。LDL是由极低密度脂蛋白(VLDL)演化而成,对于其结构,目前为人们普遍接受的是乳状液颗粒模型。作为LDL中的主要载脂蛋白apoB-100,其一级结构已经为人们所知,而高级结构的研究也得出了不少有益的结论。此外,本文还对LDL上受体结合部位和LDL受体上LDL结合部位等方面做了简单叙述。
【Abstract】 Structure and formation of low density lipoproteins (LDLs) were summarized. LDLs were derived from very low density lipoprotein (VLDLs). Emulsion particle model was established for LDLs. Primary sequence of apolipoprotein B-100 was well known and many conclusions have been obtained about secondary and tertiary structure of apoB-100. In addition, receptor-binding domains on LDLs and LDL-binding domains on LDL receptors were also described.
【关键词】 低密度脂蛋白(LDL);
载脂蛋白apoB-100;
结构;
【Key words】 Low density lipoprotein (LDL); Apolipoprotein B-100; Structure;
【Key words】 Low density lipoprotein (LDL); Apolipoprotein B-100; Structure;
【基金】 973计划资助项目; 课题编号: G1999064707
- 【文献出处】 离子交换与吸附 ,Ion Exchange and Adsorption , 编辑部邮箱 ,2001年05期
- 【分类号】O629
- 【被引频次】23
- 【下载频次】460