【摘要】 目的 了解2型DM患者的抑郁焦虑状况和选择性5 -羟色胺回收抑制剂百忧解干预治疗的效果。方法 用抑郁自评量表 (SDS)和焦虑自评量表 (SAS)对76例2型DM进行抑郁焦虑状况的评价 ,同时对SDS和 (或 )SAS积分大于41的患者进行单盲对照 ,12例用百忧解治疗3个月。结果 2型DM患者SDS、SAS评分与我国常模比较明显增高 (p<0.01) ;经3个月的百忧解治疗 ,使用百忧解的患者SDS和SAS评分较安慰剂明显改善 (p<0.05) ,血糖代谢亦有好转 (p<0.05)。结论 2型DM患者存在情绪障碍 ,而百忧解使患者的焦虑和抑郁症状得到改善 ,并有利于糖尿病病情的控制。更多还原

【Abstract】 Objective To explore the depressive-anxiety status of type 2 diabetic mellitus (DM) patients and effects of fluoxetine. Methods SDS and SAS were used to survey 76 patients with type 2 DM. Those whose SDS and (or) SAS scores exceeded 41 were randomly divided into the fluoxetine group or placebo group. Results SDS and SAS scores of DM patients were significantly higher than the domestic pattern (p<0.01). After 3 months treatment, fluoxetine group showed a significant fall in SDS and SAS score (p<0.05) and better carbohydrate metabolism. Conclusion Type 2 diabetic patients had emotional disturbances, and fluoxetine could ameliorate the disturbances and also carbohydrate metabolism.更多还原