【摘要】 目的　 观察倍他乐克对扩张型心肌病的临床疗效。方法　 将 80例病人随机分为两组 ,A组为治疗组 ,在内科常规治疗基础上给予倍他乐克 6 .2 5～ 2 5mg ,2次 d ,口服 ;B组为对照组 ,给予内科常规治疗。用药后 1个月、3个月、6个月分别观察心功能各项指标。 结果　 ①A组心功能改善总有效率 87.5% ,B组总有效率 6 7.5% ,两者相比有显著性差异 (P <0 .0 5)。②超声心动图 ,LVEDDA组较B组明显缩小 (P <0 .0 5) ;A组LVEF比B组LVEF有显著提高 (P <0 .0 5)。结论　 倍他乐克治疗扩张型心肌病需长程疗法 ,才能明显改善心功能 ,提高病人的生存质量。更多还原

【Abstract】 Objective To observe the clinical therapeutic effectiveness of metoprolol on ectatic cardiomyopathy.Methods 80 patients were divided into two groups randomly.Group A as the therapeutic group were given oral administration of metoprolol(6.25mg～25mg) twice a day based on the internal routine treatment.Goup B as the control group were only given internal routine treatment.Different indexes of cardiac functions were observed respectively one month,three months and six months after the administration of the medicine.Results The total effective rate based on the improvement of cardiac functions was 87.5% in Goup A and 67.55% in Group B with remarkable differences between the two groups(P<0.05).According to the ultrasonic cardiogram,LVEDD in Group A decreased more obviously than that in Group B and LVEF in Group A increased more obviously than that in Group B(P<0.05).Conclusion The treatment of ectatic cardiomyopathy with metoprolol needs long-term therapy so as to improve the cardiac functions remarkably and enhance the survival quality of the patients.更多还原