【摘要】 目的 :探讨非胰岛素依赖型糖尿病 (2型糖尿病 )患者心血管自主神经功能与 QT离散度 (Q Td)、JT离散度 (JTd)和室性心律失常发生的关系。方法 :2型糖尿病患者 31例 ,按照标准心血管自主神经功能试验的结果分成阳性者及阴性组 ,16例健康人为正常对照组。所有入选人员均测 QTd、JTd及 2 4h Holter心电监测 ,并进行心律失常分析和比较。结果 :2型糖尿病患者心血管自主神经功能异常的发生率为 5 4.8% ,其发生率与病程呈正相关 ,QTd与 JTd显著延长 ,室性心律失常的发生率较高。结论 :QTd和 JTd可作为一项 2型糖尿病自主神经功能异常者发生室性心律失常重要的预测指标更多还原

【Abstract】 Objective:To investigate the relation amon g cardiovascular autonomic function(CAF), QT dispersion (QTd), JT dispersion (JTd) and ventricular arrhythmias in noninsulin-dependent diabetes mellitus (NIDD M) patients.Methods:Thirty-one patients with NIDDM and 16 healthy con trol were involved in this study. According to the results of standard test of CAF, the NIDDM patients were divided into two groups: DAN + group (patients with diabetes autonomic neuropathy) and DANˉgroup(patients without diabetes aut onomic neuropathy). All the people finished 24 hours Holter test in the study and QTd and JTd were also measured to assess the occurence of ventricular arrhy thmias.Results:The positive rate of diabetes autonomic neuropathy in NIDDM patients was 54.8%, which was correlated with duration of diabetic history. Compared with those in controls and DAN - group, QTd and JTd in pati ents of DAN + group were significantly increased, and the morbidity of ventric ular arrhythmias was higher. Conclusion: QTd and JTd may be important predictors of ventricular arrhythmia in patients with NIDDM autonomic neuropathy.更多还原