【摘要】 目的 :探讨肺炎衣原体 ( CP)感染与冠心病 ( CHD)的相互关系及其对脂质代谢的影响。方法 :用多聚酶链反应 ( PCR)技术测定 5 4例 CHD患者 ( CHD组 )及 2 0例健康体检者 (对照组 )血清 CP,同时用全自动生化分析仪测定血清总胆固醇 ( TC)、甘油三酯 ( TG)、载脂蛋白 A、载脂蛋白 B浓度。结果 :CHD组 CP阳性率为 74 % ,与对照组 2 5 %相比差异有非常显著性意义 ( P <0 .0 1) ;CP阳性的 CHD患者血清 TC、TG浓度明显高于 CP阴性患者 ( P <0 .0 1)。结论 :CHD患者 CP感染率明显增高 ,CP可能通过引起脂质代谢异常而增加 CHD的危险性。更多还原

【Abstract】 Objective: To investigate the relation between chlamydia pneumoniae (CP) and coronary heart disease (CHD) and their effects on lipid metabolism.Method: CP(PCR) was diagnosed and total cholesterol (TC), triglyceride (TG), apolipoprotein A(apo A), apolipoprotein B(apo B) were measured in 54 cases of CHD, and in 20 healthy control subjects.Result: The rate of seropositive for CP in CHD patients was significantly higher than that of controls (74% vs 25%, P< 0.01 ).The patients who were CP positive had significantly (P< 0.01 ) higher TC and TG than those who were CP negative.Conclusion: CHD patients has high infectious rate of CP. CP may increase the risk of CHD by inducing the abnormal lipid metablism.更多还原