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超低温保存自体颅骨植入术42例分析

Analysis of 42 cases implanting with autoskull stored utra-hypothermia skull bone of oneself

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【作者】 朱毅梁玉峰刘鸿里崔军阳赵忠泽

【Author】 ZHU Yi, LIANG Yufeng,LUI Hongli,et al. Department of Neurosurgery, Shenyang Brain Hospital ,Shenyang 110041,China

【机构】 沈阳脑科医院神经外科沈阳脑科医院神经外科 110041110041

【摘要】 目的 分析 42例超低温保存自体颅骨植入术的优越性。方法 对 42例患者进行术后观察及随访。结果 切口均Ⅰ期愈合 ,具有生物活性和美观的效果 ,无排斥反应和免疫反应 ,不易感染等优点。冷冻 1、3、6及 12个月后选取的颅骨标本 ,电镜下组织结构与新鲜颅骨标本组织结构大致相同 ,未见颅骨细胞破坏。颅骨修补术前移植骨瓣的细菌培养均为阴性。术后随访 3~ 12个月 ,平均 6 .5个月 ,所有病例均无并发症发生。头颅X线及头颅螺旋CT检查 ,12个月后均达骨性愈合。结论 超低温保存自体颅骨再植术是修补颅骨缺损的最有效方法之一。

【Abstract】 Objective To analyze the superiority of implanting operation with autoskull stored at ultrahypothermia over low temperature’s and frozen skull bone of oneself.Methods 42 case were observed and followed up after operation.Results Incision is healing by firct intention.there were many advantages,such as good biological activity,beautiful appearance,no repellent response,no immunoreaction and hard to infection,etc. After storing 1,3,6 and 12 months,the histological structure of frozen skull observed by electronscope was similar to those of fresh skull.Pestroyed skull bone cells were not found.All cases had no complication during the period of 3 to 12 months(mean 6.5 months) follow-up after operation.After 12 months,X ray and CT scan showed that skulls were healed.Conclusions Implanting operation with autoskull stored at ultra-hypothermia is one of the most effective technique for repairing skull defects.

【基金】 沈阳市政府重大立项资助项目 (编号 9849350 4 2 1 )
  • 【文献出处】 临床外科杂志 ,Journal of Clinical Surgery , 编辑部邮箱 ,2001年06期
  • 【分类号】R651.1
  • 【被引频次】20
  • 【下载频次】32
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