【摘要】 目的 :研究垂体腺瘤患者血浆和肿瘤组织中的神经肽Y(NPY)浓度与垂体腺瘤的关系。方法 :放射免疫分析方法测定 3 3例垂体腺瘤组织和 2 0例病人血浆的NPY浓度。结果 :不同类型垂体腺瘤组织中NPY含量有显著差别 ,侵袭性垂体腺瘤NPY含量高于非侵袭性垂体腺瘤。肿瘤组织与血浆NPY水平呈正相关。结论 :不同类型垂体腺瘤组织和血浆中NPY含量有显著差别 ,NPY水平可作为垂体腺瘤侵袭性的参考指标之一更多还原

【Abstract】 Aim:To investigate the plasma and tumor tissue neuropeptide Y (NPY) concentration in patients with pituitary adenoma in relation to tumor progression. Methods:Thirty three tumor tissues and twenty plasmas of NPY were measured by radioimmunoassay in the human pituitary adenomas. Results:There was a distinctive difference of the level of NPY in different type of pituitary tumor. The invasive group had a higher level of NPY than that of noninvasive group. The NPY level in pituitary tumor tissues has a positive relationship with that in plasma. Conclusion:There was a distinctive difference of the level of NPY in different types of pituitary tumor and plasma which can be taken as an indicator to evaluate the tumor invasive potential.更多还原