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口服特比萘芬治疗儿童头癣的开放性研究

The opening study of oral terbinafine in the treatment of tinea capitis in children

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【作者】 张雅洁张桂梅熊峰季卉

【Author】 ZHANG Ya-jie,ZHANG Gui-mei,XIONG F eng,JI Hui (Department of Dermatology,Shenzhen Peoples Hos-pital,Jinan Medical University,Shenzhen,518020China)

【机构】 暨南大学医学院附属二院暨南大学医学院附属二院 深圳市人民医院皮肤科广东深圳518020深圳市人民医院皮肤科广东深圳518020

【摘要】 将符合入选标准的52例儿童头癣患者进行真菌培养,经鉴定以亲动物性犬小孢子菌为主要致病菌。采用特比萘芬口服治疗4周后临床和真菌学治愈率分别为68.9%和83.1%;治疗6周后分别为82.9%和97.4%;停药后4周则分别为90.2%和100%。治疗期间无明显副作用。

【Abstract】 The cultural examination was performed on 52cases of tinea capitis in chi ldren according to the selecting sta ndard.The results showed that the main pathogenic fungus was zoophilic Microsporum canis(64.7%).The oral dose of terbinafine depend ed on the body weight.After 4weeks treatm ent,the clinical and fungal cure rates were 68.9%and 83.1%respectively.After 6weeks treatment is 82.9%and 97.4%respectively.While 4weeks after treatment ,these rates were 90.2%and 100%resp ectively.There was no obvious side effects during th e therapy.

【关键词】 儿童头癣特比萘芬
【Key words】 ChildrenTinea capitisTerbinafine
  • 【文献出处】 临床皮肤科杂志 ,Journal of Clinical Dermatology , 编辑部邮箱 ,2001年05期
  • 【分类号】R756.1
  • 【被引频次】5
  • 【下载频次】56
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