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氟哌啶醇对精神分裂症细胞免疫功能的影响

The effect of haloperidol on cellular immunity in schizophrenics

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【作者】 张衍军马照红赵逢玉

【Author】 Zhang Yanjun,Ma Zhaohong,Zhao fengyu.Jining Veterans’ Mental Hospital,Shandong 272101

【机构】 济宁市复退军人精神病院济宁市复退军人精神病院 272101山东衮州272101山东衮州

【摘要】 目的 :探讨氟哌啶醇对精神分裂症细胞免疫功能的影响。 方法 :将入组病人用氟哌啶醇进行为期 12周的治疗 ,治疗前、后测定 T淋巴细胞亚群 CD3 、CD4、CD8阳性细胞数和红细胞免疫功能C3 b花环率 (RBC- C3 b)及红细胞免疫复合物花环率 (RBC- IC)。 结果 :疗前 CD3 、CD4、CD8、RBC- IC明显低于对照组 ;疗后 CD3 、CD4、CD4/ CD8比值、RBC- C3 b明显升高 ,CD8、RBC- IC明显降低。 结论 :氟哌啶醇对精神分裂症细胞免疫功能有明显影响

【Abstract】 Objective: To investigate the effects of haloperidol on cellular immunity. Method:Patients were treated with haloperidol for 12 weeks.Subgroup of T lymphocytes and immune function of RBC (RBC C 3b?RBC IC) were determined before and after the therapy. Results:Before the treatment CD 3,CD 4,CD 8 and RBC IC were lower than normal controls.CD 3,CD 4,CD 4/CD 8 and RBC C 3b were obviously elevated after the therapy,CD 8 and RBC IC were obviously lower after the therapy. Conclusion:The effects of haloperidol therapy on cellular immunity in schizophrenia were obvious.

  • 【文献出处】 临床精神医学杂志 ,Journal of Clinical Psychological Medicine , 编辑部邮箱 ,2001年06期
  • 【分类号】R749.3
  • 【被引频次】1
  • 【下载频次】30
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