【摘要】 目的　探讨眼眶郎格罕斯细胞组织细胞增生症影像学表现。材料与方法　回顾性分析资料完整的 12例眼眶郎格罕斯细胞组织细胞增生症 ,均行CT扫描 ,其中 6例行MRI检查。结果　主要临床表现为突眼。常见部位为眼眶外上壁、上壁及外壁。HRCT表现均呈溶骨性破坏 ,边界清楚但无硬化 ,伴大的软组织肿块 ;MRI表现T1WI均呈低信号 (与脑实质比较 ,以下同 ) ,T2 WI呈等或高信号。CT及MRI显示病变中～重度强化。结论　HRCT可清楚显示眼眶郎格罕斯细胞组织细胞增生症的骨质改变 ,能帮助临床诊断 ;MRI可准确判断病变范围 ;两者结合在本病的诊断、治疗及随访中起重要作用。更多还原

【Abstract】 Objective To explore the imaging features of orbital Langerhans’ cell histiocytosis.Materials and Methods CT and MRI findings in 12 patients with orbital Langerhans’ cell histiocytosis were retrospectively analyzed. CT scanning was performed in all 12 cases, while MRI in 6 cases.Results The commonest clinical manifestation was exophthalmos. On HRCT, osteolytic destruction with large soft tissue mass at superolateral, superior or lateral orbital wall could usually be revealed. The lesions showed well defined margin without osteosclerosis. Compared with the cerebral parenchyma, the lesions displayed hypo intensity signal on T 1WI and iso intensity or hyper intensity signal on T 2WI. On enhanced CT and MRI, the lesions showed moderate to marked enhancement.Conclusion HRCT can clearly demonstrate the bony destruction caused by Langerhans’ cell histiocytosis, which is helpful in making diagnosis. MRI can help correctly judge the lesion’s extent. A combination of CT and MRI is of great value in the diagnosis, treatment and follow up of orbital Langerhans’ cell histiocytosis.更多还原