【摘要】 目的 :研究银络丹 (yingluodan ,YLD)的急性毒性及抗移植性肿瘤生长作用。方法 :测定YLD半数致死量LD50 ,并采用小鼠移植性肿瘤实验法观察YLD抗肿瘤生长活性。结果 :YLD小鼠灌胃LD 5 0为 5 1.1mg/kg ,YLD10mg/kg剂量组艾氏腹水癌 (EAc)小鼠存活时间比对照组显著延长 ,生命延长率超过 30 %。结论 :YLD对小鼠移植性艾氏腹水癌生长有明显的抑制作用更多还原

【Abstract】 Objective: To investigate the acute toxiticy and anti-cancer effect of Yingluodan (YLD).Methods:The anti cancer activity of YLD was determined by using mice′s transplanting cancer (EAC) model and its LD 50 was also measured. Results:mice′s LD 50 by ig was 51.1 mg/kg.Survive time of the group of 10mg/kg by ig increased significantly.Life extending percent surpassed 30%.Conclusion:YLD have significant theraputic efficacy in mice′s transplanting cancer.更多还原