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50岁以上无前列腺癌老年人血清中的PSA水平调查

A investigation of seram prostate specieic antigen levels in men older than 50 years without clinical evidence of prostatie cancer

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【作者】 周锦春余红兵张明富

【Author】 Zhou jinchun Yu Hongbing Zhang Mingfu Department of clinical Laboratory Tongji Hospital affiliated to Tongji Medical College of Huaznong University of Science and Technology Wuhan 430030 

【机构】 武汉同济医科大学附属同济医院检验科

【摘要】 目的 对于50岁以上无前列腺癌老年人,确定血清的前列腺特异性抗原(Prostate Specific Antigen PSA)水平的范围。 方法 以每隔10岁为一年龄段,检测104例无前列腺癌男性的血清,取平均值(x)和标准差(s)。 结果 血清中PSA水平分别为:50~59岁组1.32±1.10ng/ml;60~69岁组1.91±1.72ng/ml;70~79岁组2.36±1.98ng/ml。各年龄组PSA水平最大值(x+2s)分别为3.5ng/ml、5.4ng/ml、6.3ng/ml。 结论 新的上限值对60~69岁的准确性较高,而对70~79岁组准确性较低。更大规模地重复并改进实验方法,解决PSA上限值的不准确性,可使PSA值与年龄的关系更有效地适用于临床。

【Abstract】  Objective To determine the ranges of serum prostate specific antigen PSA level in men older than 50 years without clinical evidence of prostate cancer. Methods The mean and standard deviation were readed by detecting serum PSA levels in 104 men older than 50 years according to age decade. Results Serum PSA levels were 1.32±1.10ng/ml in the 50 to 59-year group 1.91±1.72ng/ml in the 60 to 69-year group and 2.36±1.98ng/ml in the 70 to 79-year group respeetively. The upper limits for PSAx+2s by age were 3.5ng/ml in the 50 to 59-year group 5.4ng/ml in the 60 to 69-year group and 6.3ng/ml in the 70 to 79 year group respectively Conclusions The accuracy of new limits was higher in the 60 to 69-year group than that of the next decade group. To resolve the problem of accuracy by repetition of this study on a larger scale and improving the method can adapt the correlation between PSA ranges and age for more efficient in clinical cases. 

【关键词】 前列腺特异性抗原前列腺癌
【Key words】 Prostatespecificantigencancer
  • 【文献出处】 江西医学检验 ,Jiangxi Journal of Medical Laboratory Sciences , 编辑部邮箱 ,2001年02期
  • 【分类号】R737.25
  • 【下载频次】13
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