【摘要】 本文报道了中国第 1 6次南极考察队 (长城站 )队员赴南极前和在南极居留一年二周返回国内后 ,血中甲状腺素和儿茶酚胺含量的变化 ,以探讨考察队员在居留南极期间普遍存在的生理和心理变化的物质基础。 1 6次队 1 0名男性考察队员血样分别用化学发光法检测血清总甲状腺素 (TT3、TT4)和促甲状腺激素 (TSH)的含量 ,用高效液相色谱 -电化学法测定血浆中肾上腺素(E)、去甲肾上腺素 (NE)和多巴胺 (DA)的含量。结果表明 :长城站 1 6次队 1 0名男性考察队员赴南极前和在南极居留一年二周返回国内后相比 ,血清中甲状腺素TT3含量无显著性差异 ,TT4含量有非常显著性降低 (P <0 0 1 ) ,促甲状腺激素TSH含量有非常显著性升高 (P <0 0 1 ) ;血浆中的NE、DA含量无显著性差异 ,E的含量有显著性降低 (P <0 0 5 )。南极特殊环境对考察队员甲状腺功能具有减退作用 ;对肾上腺髓质E在血浆中含量有降低作用 ;甲状腺和肾上腺髓质系统共同参与南极综合应激反应 ,以调节机体与外界的平衡。更多还原

【Abstract】 The changes of serum thyroid hormone total thyroxine (TT4), triodothyronine (TT3), thyroid stimulating hormone (TSH) and plasma catecholamine,including norepinephrine (NE), epinephrine (E), dopemine (DA) were investigated in 10 male Antarctic expedition members (in Great Wall Station) under extreme environmental condition by CLIA and HPLC ECD. Samples were taken at different time: (1) before leaving to Antarctica (2) returned to China after living 1 year and 2 weeks in Antarctica. Comparing of before leaving and returned, results showed that there was a significant decrease in the contents of TT4 (P<0.01), with no significant change in the content of TT3. It was also found that the content of TSH increased significantly (P<0.01); No significant changes of plasma NE and DA were found,but the content of E decreased significantly (P<0.05). The results indicated that the special Antarctic environment led to a restrain effect on the thyroid function and the level of plasma E in Antarctic expedition members. Both the thyroid and adrenal system were associated in response to the Antarctic systemic stress to maintain the balance between human bodies and environments.更多还原