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《中国药房》临床随机对照及药动学试验文献方法学评价

Methodological Evaluation of Randomized Controlled Trials Published in Journal of China Pharmacy from 1990-2000

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【作者】 费小凡任雪松李开兰杨利平苏兰彭英刘春雨

【Author】 FEI Xiao-fan,REN Xue-song,LI Kai-lan,et al. (Department of Pharmacy,First University Hospital,West China University of Medical Sciences,Chengdu 610041,China)

【机构】 华西医科大学附属第一医院药剂科!四川成都610041攀枝花矿务局总医院!四川攀枝花617066长钢总医院!四川江油621701华西医科?

【摘要】 目的 :了解《中国药房》从 1990年至 2 0 0 0年间随机对照试验论文的设计和撰写现状。方法 :逐期逐页手工检索《中国药房》 1990~ 2 0 0 0年中发表的对照试验 ,按Cochrane协作网RCT、CCT资料库中的判定标准进行严格鉴定。结果 :在 11卷 6 6期中共刊登临床对照试验 6 3篇 (其中RCT只有 1篇 ) ;药动学对照试验 46篇 (其中RCT有 2篇 )。结论 :《中国药房》刊登的临床对照试验论文存在较多问题 ,其质量还有待提高。

【Abstract】 Objective:To realize the quality of the ethics of the randomized controlled trials in Chinese Pharmacy from 1990 to 2000.Methods:It was checked over page-by-page the control trials of clinical therapeutic studies in Chinese Pharmacy from 1990 to 2000 to identify strictly randomized controlled tests(RCT)and controlled clinical tests(CCT)according to the criteria of the handbook of Cochrane collaboration in 1997.Result:A trial of 63 articles on clinical trials was published in 66 issues covered 11 volumes of the Chinese Pharmacy,among which,there were 1 issues of RCT.Conclusion;There still exist many problems and urge the clinical workers to adopt RCT and blind trial as more as possible and guarantee RCTs to be precise as it demands.

【关键词】 中国药房随机对照药动学
【Key words】 Chinese PharmacyRandomized Controlled Trials
  • 【文献出处】 华西医学 ,West China Medical Journal , 编辑部邮箱 ,2001年02期
  • 【分类号】R-5
  • 【下载频次】41
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