【摘要】 目的 :探讨氟罗沙星注射液在自然光和不同灯光照射下的稳定性 ,以找出不同光源对该药物稳定性的等效关系。方法 :采用了室温下自然光和不同灯光进行光照加速实验的方法。结果 :该药在光照试验中颜色变化遵从零级动力学规律 :A =A0 +κ·Et。结论 :根据不同光源照射下的吸光度与光照量的关系 ,求得使药物降解到某种程度时 ,不同光源光照量之间的等效数量关系更多还原

【Abstract】 OBJECTIVE:The effect of lamplight and daylight on the stability of fleroxacin injection was studied.METHODS:Accelerated tests upon exposure to light were employed.RESULTS:The photodegradation of fleroxacin injection obeys zero kinetics:A=A 0+ k·Et .CONCLUSION:The equivalent influences between daylight and UV mercury arc lamplight , fluorescent mercury arc lamplight, tungsten lamplight were obtained. Therefore, the daylight photostability can be conveniently obtained from lamplight exposure experiments.更多还原