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家兔急性实验性面神经损伤的组织病理观察

Histopathological Observation of Acute Facial Nerve Impairment in Rabbits

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【作者】 王恺徐丽蓉罗德儒肖邦良

【Author】 Wang Kai* ,Xu Lirong,Luo Deru, Xiao Bangliang. * Department of Otolaryngology,The First Affiliated H ospital,WCUMS,Chengdu6 10 0 41, China

【机构】 华西医科大学附属第一医院耳鼻咽喉科!成都610041华西医科大学附属第一医院神经内科华西医科大学公共卫生学院卫生毒理研究室

【摘要】 目的 观察家兔面神经急性损伤后髓鞘和轴索的组织病理变化。方法 用丝线结扎茎乳孔以外的面神经总干 ,观察结扎后 1天、3天及 5天面神经的组织病理改变。结果 家兔面神经受损后 ,先后在髓鞘和轴索出现轻重不等、程度不同的形态学改变。结论 结扎家兔面神经后 ,其髓鞘及轴索会出现相应的病理改变 ,且随着结扎天数的增加 ,面神经损伤亦呈加重的趋势

【Abstract】 Objective To investigate histopathological changes of acute facial nerve im pairm ent.Methods L igation of facial nerve outside stylom astoid foramen with 3- 0 silk,observation of histopathological changes of facial nerve on the1st day,3rd day and5 th day after ligation.Results The facial nerve showed all kinds and various degrees of histopathological changes,from swelling to degeneration,in m yeline and axon respectively. Conclusion All kinds and various degrees of pathological changes have been observed in m yeline and axon after the ligation of facial nerve in rabbits.This study demonstrates that such injuries to the facial nerve become increasingly serious as the ligation lasts day after day.

  • 【文献出处】 华西医科大学学报 ,Journal of West China University of Medical Sciences , 编辑部邮箱 ,2001年01期
  • 【分类号】R745.12
  • 【被引频次】11
  • 【下载频次】119
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