【摘要】 本文应用前列腺素E1治疗慢性乙肝患者 2 8例 ,分别于治疗前和治疗结束时抽血查血清谷丙转氨酶(GPT)、血清总胆红素 (TBIL)、血清总胆汁酸 (TBA)、透明质酸 (HA)和前Ⅲ型胶原 (PCⅢ )。治疗 1个月后 ,观察组GPT ,TBIL ,TBA ,HA及PCⅢ治疗前后相比差异具有显著性 (P <0 .0 5 ) ,和对照组相比差异也具有显著性 (P <0 .0 5 )。提示PGE1能明显改善慢性乙肝患者肝功能 ,并具有一定的抗肝纤维化作用。更多还原

【Abstract】 To search for an effective drug to cure patients with chronic hepatitis B. Twenty eight patients with chronic hepatitis B were treated with prostaglandin E 1. The comprehensive indexs, including glutamic pyruric tranasaminase (GPT), serum total bilirubin (TBIL), total bile acid (TBA), hyaluronic acid (HA) and precollagen type Ⅲ (PCⅢ), were examined before and after treatment. The levels of GPT, TBIL, TBA, HA, PCⅢ after 1 month of the treatment were significantly lower than those before the treatment (P<0.05), there were significant differences between the treated and the controlled group patients with chronic hepatitis B (P<0.05). The results suggest that the treatment with PGE 1 might improve hepatic function, and resist the hepatic fibrosis in patients with chronic hepatitis B.更多还原