【摘要】 目的 :检测催乳素在妊高征中的水平及与妊高征的关系。方法 :选择正常妊娠妇女 89例及妊高征患者5 2例 ,分区方法 ,按妊娠每 2周分为 8组 ,按正常妊娠每组的催乳素均值划分 3区 ,即A区 (高值区 ) (> x +s) ;B区(中值区 ) ( x +s)～ x ;C区 (低值区 ) x～ ( x +s) ;利用放射免疫分析法测定正常妊娠中晚期及妊高征催乳素水平。结果 :正常妊娠第 2 4周催乳素均值为 2 70mg·L-1,随孕周增加而升高 ,第 34～ 37周达高峰 ,峰值为 44 0mg·L-1,后逐渐下降。妊高征组血清催乳素显著高于正常妊娠组 ;其中 31例 (5 9.6 % )催乳素在A区 ,10例 (19.3% )在B区 ,11例(2 1 1% )在C区。结论 :高催乳素水平可能与妊高征发病有关。更多还原

【Abstract】 Objective: This study was to investigate the relationship between serum prolactin and pregnancy induced hypertension. Method: Maternal serum prolactin was estimated by radioimmunoassay in 89 normal pregnant women and 52 patients with severe pregnancy induced hypertension at 28 to 42 week gestation. Results: In normal pregnancy, prolactin level increased progressively from a mean value of 270 mg·L -1 in the 24th week to 440 mg·L -1 in the 34th week and decreased progressively from the 38th week to the 40th week. In severe pregnancy induced hypertension increased progressively too;31 of 52 patients with severe prolactin showed high prolactin levels in zone A(>mean value + standard of prolactin values in the normal pregnancy),10 patients in zone B(mean+standard to mean )and 11 patients in zone C(<mean).Conclusion:These results suggest that high prolactin levels may play an important role in the pathogenesis of severe pregnancy induced hypertension. [更多还原