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自身抗体与复发性流产的关系

The relationship between some autoantibodies and recurrent spontaneous abortion

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【作者】 毛立群李瑞民闫燕华

【Author】 MAO Li-qun, et al (Department of Immunology and Microbiology, Medical College of Chinese People’s Armed Police Forces Tianjin 300162, China)$$$$

【机构】 武警医学院微生物与免疫教研室承德医学院微生物教研室天津医科大学免疫教研室 天津300162河北承德067000天津300070

【摘要】 目的 :探讨自身抗体与复发性流产的关系。方法 :采用酶联免疫吸附法 (ELISA)对 30例不明原因的复发性流产 (URSA)患者进行抗心磷脂抗体 (ACA)和抗血小板抗体 (PA)的检测 ,并与正常人进行比较。结果 :URSA组ACA~IgG、ACA~IgM或和PA~IgG的阳性率分别为 4 3.33%、30 .0 0 %和36 .6 7% ,与正常对照组相比有显著性差异。结论 :这些自身抗体的出现可能与流产有关。

【Abstract】 Objective: To study on relationships between some autoantibobies and recurrent spontaneous abortion. Method: Anticardiolipin antibody (ACA) and platelet associated immunoglobulin (PA ) was measured by enzyme linked Immunosorbent assay (ELISA) inperipheral blood of 30 women with unexplained recurrent spontaneous abortion(URSA). Results: The percents of ACA-IgG, ACA-IgM and PA-TgG among women with URSA were 43.33%, 30.00% and 36.67%. Compared with those in the normal control, they were increased (P<0.01, P<0.01, P<0.05). Conclusion: The increasing of ACA-IgG,ACA-IgM and PA-IgG may be associated with the occurrence of URSA.

  • 【分类号】R714.21
  • 【被引频次】8
  • 【下载频次】106
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