【摘要】 以 1 ,3-二氯 -2 -丙醇及 N,N -二对甲苯磺酰胺 ( 2 a,2 b)为起始原料 ,通过关环反应合成新化合物 ( 3a,3b) ,然后脱去 3a,3b的对甲苯磺酰基 ,得到标题化合物 ( 4a,4 b)。本文从分子内与分子间反应的竞争及反应物2 a,2 b的分子结构两方面讨论了对关环反应产率的影响更多还原

【Abstract】 Starting from 1,3 dichloro 2 propanol and di N tosylamides(2a,2b), the corresponding new cyclic compounds(3a,3b) were synthesized by cyclization reaction. Then the Ts groups of 3a and 3b were removed to get the heading compounds 4a,4b. The effects of the competing reactions between the intramolecular condensation and the intermolecular condensation and the structure of 2a,2b to the yields of 3a, 3b were discussed.更多还原