【摘要】 目的　探讨肾病综合征 (NS)患儿生长迟缓及相关因素。方法　对 3 3例肾病综合征患儿计算身高标准差积分 ,对患儿血钙、骨碱性磷酸酶 (BALP)、2 5 羟维生素D3[2 5 (OH)D3]、生长激素 (GH)、甲状旁腺素 (PTH)水平进行测定。结果　NS患儿血钙偏低 (P <0 .0 1 ) ,GH、2 5 (OH)D3较对照低 (P均<0 .0 5 ) ,PTH、BALP水平较对照组高 (P均 <0 .0 1 )。患儿的身高标准差积分 (HtSDS)降低。且与病程长短 ,激素累积使用量成密切相关。结论　NS患儿存在生长发育迟缓及钙代谢和内分泌代谢紊乱更多还原

【Abstract】 Objective To study the growth obstruction and related factors in children with nephrotic syndrome (NS).Methods In 33 children with NS,HtSOS was calculated;the concentration of serum calcium,BALP,25(OH)D 3,PTH,GH were measured.Results Serum calcium levels were significantly lower (P<0.01);concentration of serum HG and 25(OH)D 3 significantly decreased (P<0.05,P<0.01);concentration of serum BALP and PHT markedly increased (P<0.01).HtSDS of patients decreased,which was closely related to the duration of disease and hormone accummulated dosage.Conclusion There were dysfunctions of the calcium and endocrine metabolism in children with nephrotic syndrome,which obstructed the children’s growth.更多还原