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仔猪水肿病多价油乳剂灭活菌苗在猪体内的免疫原性研究
Immunogenicity of Piglet Oedema Disease Multivalent Oil emulsion Inactivated Vaccine in Piglets
【摘要】 用自制的仔猪水肿病多价油乳剂灭活菌苗肌肉注射 2 0日龄未接种同类疫苗的长杂健康仔猪 ,1 4d后用攻毒菌株 (湖北地方分离株及O1 38、O1 39、O1 4 1 3个菌株 )攻毒。结果表明每头免疫剂量为 0 .50mL (含 30亿CFU)免疫效果最好 ,免疫 2周后血清抗体几何凝集效价为 1∶640 ,保护率达到 1 0 0 %。
【Abstract】 Intramuscular injection of 20 day old healthy Changza piglets without inoculating similar vaccine with piglet oedema disease multivalent oil emulsion inactivated vaccine was carried out.the piglets were challenged with Hubei local isolated strains and O 138 ,O 139 and O 141 .Results showed that 0.50 mL(containing 30×10 8 CFU) immune dose per piglet had the best effect, and two weeks later the piglets’ serum antibody geometric agglutination titer reached 1∶640, protection rate reached 100%.
【关键词】 仔猪水肿病;
多价油乳剂灭活菌苗;
免疫原性;
【Key words】 oedema disease of piglet; multivalent oil emulsion inactivated vaccine; immunogenicity;
【Key words】 oedema disease of piglet; multivalent oil emulsion inactivated vaccine; immunogenicity;
【基金】 湖北省教委资助项目
- 【文献出处】 湖北农学院学报 ,Journal of Hubei Agricultural College , 编辑部邮箱 ,2001年01期
- 【分类号】S852.52
- 【被引频次】5
- 【下载频次】60