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ETEC多价定居因子对仔猪大肠杆菌病的预防试验
Protection Against Piglets Colibacillosis with Polyvalent Resident Factors of Enterotoxigenic Escherichia Coli
【摘要】 应用分子免疫学理论 ,将定居因子K88,K99,987P ,F4 1与其特异受体结合 ,封闭肠粘膜上皮细胞的受体 ,阻断致病菌的定居因子与肠粘膜上皮细胞特异受体的结合 ,使致病菌无法定居。试验结果显示 ,其仔猪攻毒保护率为 10 0 % ,预防试验保护率为 10 0 % ,可以有效控制仔猪大肠杆菌的发生 ,为该病的现有预防模式增添了新的内容
【Abstract】 The resident factors K88,K99,987P and F41 had been combined with the specific receptors of the intestinal mucosa epithelial cells under the molecular immunoreaction,and the specific receptors had been blocked.The receptors blocked by resident factors couldn′t attach the resident factors,and prevented the enterotoxigenic E.coli settling down the intestine.The results showed that the piglets infected protection rate was 100%,preventive protection rate was 100%.The experiments proved that the method was effective measures against piglets colibacillosis,and added new content to preventive model at present.
【Key words】 Piglets; Enterotoxigenic E.coli; Resident factors; Prevention;
- 【文献出处】 华北农学报 ,Acta Agriculturae Boreall—sinica , 编辑部邮箱 ,2001年02期
- 【分类号】S858.28
- 【被引频次】10
- 【下载频次】57