【摘要】 目的　评估静注地塞米松 10mg对术后硬膜外吗啡镇痛引起恶心呕吐的效应。方法　 12 0例术后行硬膜外吗啡镇痛病人 ,术毕随机静注地塞米松 10mg(地米组n =60 )或生理盐水 2ml(对照组n =60 )。结果　术后 48小时内恶心呕吐发生率 :地米组 (5 4例病人中有 8例 ) 14 81% ,对照组 (5 8例病人中有 11例 ) 18 96%。两组发生率比较P>0 .0 5。结论　静注地塞米松对预防术后硬膜外吗啡镇痛引起恶心呕吐的作用不明显 ,而治疗PONV作用肯定更多还原

【Abstract】 Objective To estimate the effect of dexamethasone (Dex) intravenous injection on preventing postoperative nausea and vomiting related toepidural morphine analgesia.Methods 120 patients requring postoperative analgesia with epidural morphine were randomized into two groups.Dexamethasone 10mg(Dex group n=60) or saline (control group n=60) was administed i.v.at the end of the surgery.Results The total incidence of postoperative nausea and vomiting 14.81% in Dex group druing 48 hours after surgery and it was 18.96%in control group(P>0.05).Conclusion The effect of Dexamethasone intruvenous injection on preventing postoperative nausea and vomiting related to epidural morphine analgesia is not obvious,but it is effective to treat postoperative nausea and vomiting.更多还原