节点文献
不同类型肝炎患者及献血员血清和肝组织中TTV的检测
AN INVESTIGATION TTV IN THE SERA AND HEPATIC TISSUE OF THE DIFFERENT HEPATITIS PATIENTS AND THE BLOOD DONORS
【摘要】 目的 :探讨不同类型肝炎患者及献血员 TTV (Transfusion transm itted Virus,TTV)其感染状态及临床特征。方法 :采用斑点杂交和原位杂交方法检测不同人群共 83例及 7例不同类型肝病病人的肝组织 TTVDNA。结果 :TTV在各组肝炎病总检出率为 2 2 .9% ,7例肝组织 TTV阳性率为 2 8.6 % ,而且在非甲 -非戌型肝炎病人中检出率最高 (38.9% )。结论 :TTV在不同人群中均能检出 ,而非甲 -非戌型肝炎患者中检出率最高 ,提出 TTV可能是一种损肝病毒 ,而且可致肝重度损害。
【Abstract】 Objective:TTVDNA was an investigation in sera and hepatic tissues in different crowds to probe the infectious state and the feature of transfusion transmitted virus (TTV).Method:TTVDNA in sera and in hepatic tissue was tested with Southern Blot and Hybridization in situ respectively. Results: The positive rate of TTVDNA in the patients with virus hepatitis was 22.9%,the highest rate of TTVDNA was found in the patients with non-A-E virus hepatitis (38.9%).Conclusions:TTV could be found in sera and tissue in different crowds, especially in the patients with non-A-E.The result suggests that TTV might be a factor to injure the liver.
- 【文献出处】 广西医科大学学报 ,Journal of Guangxi Medical University , 编辑部邮箱 ,2001年03期
- 【分类号】R446.6
- 【被引频次】1
- 【下载频次】14