【摘要】 采用AMI方法研究了蒽醌衍生物的亲核取代反应活性,结果表明,在蒽醌的1-位进行亲核取代反应可以形成较稳定的反应过渡态。研究了1-氯蒽醌、1,5-二氯蒽醌与具有氨基、羟基、巯基等亲核试剂的反应,并通过熔点、液-质联用和元素分析等手段对产物进行了确认。更多还原

【Abstract】 The nucleophilic activities of anlhraquinones were studied on the basis of AMI method.. The stability of transition state in reaction was related to the substitution position on anthraquinone ring. The calculated results suggested that the anthraquinone with a leaving group at a - position had better nucleophilie activity than that with a leaving group at h - position. Reactions of 1-chloroanthraquinone and 1,5-dichloroanthraquinone with nucleophiles contaning amino, hydroxyl and mercapto groups were studied.更多还原