【摘要】 目的 :对照观察尼莫地平与脑复康治疗老年期痴呆患者 180例的临床疗效。方法 :将 180例老年期痴呆患者随机分为 2组 ,治疗组口服尼莫地平 ,对照组口服脑复康。结果 :治疗后患者简易智力状态检查量表 (MMSE)评分提高 ,日常生活能力量表 (ADL)评分下降 (P <0 .0 1)。治疗组显效率为 30 % ,总有效率为 74 .4 %。对照组显效率为 2 2 .2 % ,总有效率为 62 .2 % ,两组间比较有统计学意义 (P <0 .0 1)。结论 :改善脑循环是尼莫地平治疗老年期痴呆的机理之一 ,从而提高患者认知功能与生活能力 ,疗效肯定 ,使用安全 ,未见明显副作用更多还原

【Abstract】 Aim:To compare the efficacy of and in treating 180 cases of senile dementia.Method:180 cases in two groups,therapeutic group,oral administration with Nimodipine;control group,with Piracetamun.Result:After treating,MMSE was on the rise,ADL was down( P <0.01).Effectual rate in therapeutic group was 30%,tatal efficacy 74.4%,while in control group,the effectual rate and total efficacy were 22.2% and 62.2% respectively.The comparism was with statistical value( P <0.01).Conclusion:Improving cerebral circulation is one of the mechanisms in treating senile dementia with Nimodipine,which will improve cognition and viability.It is effective,safe,without distint side effects.更多还原