节点文献
视网膜色素变性(RP)患者的EOG异常改变
Abnormal change of the electrooculograms (EOG) in retinitis pigmentosa(RP)
【摘要】 目的 探讨RP患者眼电图(EOG)的特征以及EOG作为评估RP手术疗效的客观指标的可能性。方法 采用MVT-3型视觉电生理仪的EOG采集和分析软件,对正常对照组和RP患者组在术前与术后进行检测。结果 (1)105名RP患者的EOG曲线大体可分为两种类型,即弯曲型与平坦型。弯曲型EOG各项参数较接近正常组EOG,该组绝大部分患者的视野马斑驳状;而平坦型EOG的一些主要参数(如Arden比和G比值等),明显地低于正常组,该组患者的视野多为管状视野或视野完全缺损。(2)在进行手术后半年以上复查EOG,则一些主要参数数值增加,有的患者(34.5%)的EOG由平坦型转变为弯曲型。结论 RP患者的EOG具有为该病所特有的特征,术后随主观症状的改善,EOG异常也恢复或部分恢复,这些都可作为该病诊断以及术后疗效评估的客观指标之一。
【Abstract】 Objective To characterize the EOG of the patients with the retinitis pigmentosa (RP) and attempt to use the EOG of RP as an objective measure to assay the therapeutic effect. Methods Acquirement and analysis of EOG data were automatically performed using the EOG program of the MVT-3 visual electrophysiological equipment. Results Before surgical therapy, EOGs of 105 patiens with RP were examined.These patients’ EOG traces could be divided generally into two types, named curved and smooth. The shape and parameters of the curved EOG group were more similar to those of the normal groups. However, the main parameters of the smooth-type EOG patients were obviously lower than those of the normals, and these patients had the damage of more expansive area of their visual fields. More about half years after the surgical therapy, the eighteen patients were reexamined. The results was that the EOG traces were more curved and some of the smooth-type curves had been transferred to curved type ones, some of the EOG parameters (e.g. Arden ration and G-ratio) were increased as well. Conclusion The abnormal characteristics of the EOGs of the RP patients could be improved after surgical therapy and the EOG can be used as one of the objective measures for the diagnosis and assay on the therapeutic efficacy in the RP.
- 【文献出处】 美中国际眼科杂志 , 编辑部邮箱 ,2001年03期
- 【分类号】R774.1
- 【被引频次】5
- 【下载频次】77