【摘要】 吡柔比星在 0 .1 mol/L HAc- Na Ac缓冲溶液 (p H4.3)中 ,出现一灵敏的示波极谱导数还原峰 ,峰电位为 - 0 .39V(vs.SCE) ,峰电流与吡柔比星浓度在 2 .0× 1 0 -7～ 4.0× 1 0 -6mol/L范围内成正比。检出限为 1 .0× 1 0 -8mol/L。用于病人尿样的测定。用线性扫描和循环伏安法研究体系的性质。体系属具有吸附性的可逆过程。更多还原

【Abstract】 In a 0.1 mol/L HAc NaAc (pH 4.3) buffer solution, a sensitive reduction peak of pirarubicin was obtained by single-sweep oscillopolarography. The peak potential is -0.39 V( vs .SCE). A linear relationship is held between the peak current and pirarubicin concentration in the range of 2.0×10 -7 ～4.0×10 -6 mol/L with detection limit of 1.0×10 -8 mol/L. The method was applied to determination of trace pirarubicin in urine. The voltammetric behavior of the system was studied by linear sweep and cyclic voltammetry. The system belongs to the reversible process with adsorptive characteristics.更多还原