【摘要】 利用荧光和紫外可见吸收光谱研究了 Ru( bipy) 2 ( dppz) 2 +与 DNA之间的插入键合作用。结果表明 ,Ru( bipy) 2 ( dppz) 2 +是通过 dppz配体插入到 DNA的双螺旋结构中。而且 ,一定浓度的 Fe( CN) 4 - 6 和 Na Cl对 Ru( bipy) 2 ( dppz) 2 +- DNA复合物的荧光无猝灭作用 ,这一结果也证实了 Ru( bipy) 2 ( dppz) 2 +和 DNA之间的插入键合作用更多还原

【Abstract】 The interaction between Ru(bipy) 2(dppz) 2+ (bipy=2,2 bipyridine,dppz=dipyrido[3,2 a:2′,3′ c] phenazine) and the calfthymus DNA was studied with fluorescence and ultraviolet visible absorption spectroscopy. The ultraviolet visible absorption spectra of Ru(bipy) 2(dppz) 2+ , calfthymus DNA, and their interaction indicated that Ru(bipy) 2(dppz) 2+ intercalated into the double helix of DNA via the ligand dppz. The results of fluorescence quenching and salt effect also supported the intercalated binding mode.更多还原