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Study on Effect of Gd (III) Speciation on Ca (II) Speciation in Human Blood Plasma by Computer Simulation

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【Author】 Yue WANG, Xing LU, Shu Yun WANG, Jing Fen HAN, Kui Yue YANG, Chun Ji NIU*, Jia Zuan NI Key Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022

【Abstract】 Ca (II) speciation and effect of Gd (III) speciation on Ca (II) speciation in human blood plasma were studied by computer simulation. [CaHCO3]+ is a predominant compound species of Ca (II). Gd (III) can compete with Ca (II) for biological molecules. The presence of Gd (III) results in a increase of concentration of free Ca (II) and a decrease of concentration of Ca (II) compounds.

【基金】 the NSFC for financial support of this work (Project Nos.29890280, 29971029).
  • 【文献出处】 Chinese Chemical Letters ,中国化学快报(英文版) , 编辑部邮箱 ,2001年02期
  • 【分类号】O614
  • 【下载频次】18
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