【摘要】 目的 :探讨脑动静脉畸形 (arteriovenousmalformation ,AVM)的临床表现 ,治疗方法的选择和手术并发症的防治。方法 :总结分析近 10年收治的 6 1例脑动静脉畸形患者的临床资料。结果 :显微神经外科手术治疗共 5 0例 ,其中SpetzlerⅠ～Ⅲ级患者病灶全切率为 93 .8% ( 45 /4 8)。手术后并发症为 :术后一过性神经功能障碍患者占10 % ( 5 /5 0 ) ,较严重的神经功能障碍占 10 % ( 5 /5 0 ) ,无手术死亡。 9例行血管内栓塞治疗和 /或放疗。 2例观察。结论 :显微外科手术是脑AVM的主要治疗方法 ,对于Spetzler MartinⅠ Ⅲ级的脑AVM ,要尽量争取早期手术切除 ,其切除率高而致残率低。Ⅳ级以上的患者应行综合治疗 :外科手术、血管内栓塞和放疗更多还原

【Abstract】 Objective: To study the clinical presentations, the selections of therapeutic methods and prevention of surgical complications of brain arteriovenous malformation (AVM). Methods: Clinical materials of 61 cases with brain AVM treated surgically during the last 10 years were analyzed. Results: Fifty cases were treated by microsurgical resection. The radical resection rate for Spetzler grade Ⅰ to Ⅲ was 93.8% ( 45/48 ). Surgical morbidity was 20% ( 10/50 ), in which, half the cases were early transient nervous dysfunction, half were serious ones. Peri operative mortality was 0. Only 9 cases were treated with endovascular embolization and / or radiotherapy. Two cases had been obser ved intensively without treatment. Conclusion: Microsurgical excision is the main therapeutic modality of brain AVM. It’s necessary to be resected usrgically as early as possible for Spetzler Martin grade Ⅰ to Ⅲ for its high healing rate and low morbidity. Cases of grade Ⅳ or higher should be treated with a multimodality therapy including surgical resection, endovascular embolization and radiotherapy.更多还原