节点文献
抗原对CD8~+T细胞记忆的贡献
CONTRIBUTIONS OF ANTIGEN TO MAINTENANCE OF CD8~+T CELL MEMORY
【摘要】 基于T细胞的逆线性分化假说建立了非线性理论模型 .利用此模型 ,得出记忆T细胞逆线性分化模型确有记忆机制 ,并发现记忆强度与抗原量有直接的关系
【Abstract】 It is still debated how T cell memory is maintained. Based on the converse linear differentiation hypothesis of memory T cells, a nonlinear theoretical model is established. This model demonstrated that there exists memory mechanism on the basis of converse linear differentiation hypothesis. In the present paper, “memory strength” is introduced and the relationship between memory strength and residual antigenic doses has been studied.
【关键词】 免疫;
数学模型;
抗原;
T细胞记忆;
细胞分化;
【Key words】 immunity; mathematical model; antigen; T cell memory; cell differentiation;
【Key words】 immunity; mathematical model; antigen; T cell memory; cell differentiation;
【基金】 国家自然科学基金资助项目 !(30 0 70 2 16 )
- 【文献出处】 北京师范大学学报(自然科学版) ,Journal of Beijing Normal University(Natural Science) , 编辑部邮箱 ,2001年01期
- 【分类号】Q26
- 【下载频次】76