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高脂血症大鼠红细胞扫描电镜观察

Scanning electron microscopic observation of erythrocytes in hyperlipemia rats

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【作者】 潘力崔新明崔丽李颖栗振宝

【Author】 PAN Li,CUI Xin-ming,CUI Li,LI Ying,LI Zhen-bao (Department of Electron Microscopy,School of Basic Medical Sciences,Jilin University, Changchun Jilin 130021 China) [

【机构】 吉林大学基础医学院电子显微镜室!吉林长春130021

【摘要】 目的 :探讨高脂血症红细胞形态变化和临床意义。方法 :Wistar大鼠分为正常对照组 ( NC)和高脂血症组 ( HL,喂饲高脂饲料 ) ,利用扫描电镜观察红细胞形态改变并计数分类。结果 :与 NC组比较 ,HL组的正常红细胞百分比由 76.4 %减少到 4 5.7%、棘型红细胞、球口型红细胞、靶型红细胞分别由4 %、2 .2 %、1.5%增加到 17.3%、10 .4 %、5.8% ,嵴型和其它异型红细胞也略有增加。结论 :高脂血症的异型红细胞明显增加。

【Abstract】 Objective: To study the morphological changes of erythrocytes in hyperlipemia. Methods: Wistar rats used were divided into normal control group (NC) and hyperlipemia group (HL, fed with high lipid diets). The morphological changes of erythrocytes were observed by SEM, and classified and counted. Results: Compared with NC,percentage of normal erythrocytes in HL were decreased from 76.4% to 45.7%. The percentage of echinocytes, spherostomatocytes and target cells were increased from 4%, 2.2%, 1.5% to 17.3%, 10.4% , 5.8% respectively. The number of ridged cells and abnormal cells was a little increased.Conclusion: The number of abnormal erythrocytes was significantly increased in hyperlipemia. [

  • 【分类号】R589.2
  • 【被引频次】15
  • 【下载频次】163
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