【摘要】 目的 :探讨晚期卵巢癌合并腹水的正确处理方法。方法 :A组 (6 0例 )术前腹腔化疗 2～ 3次 ,静脉化疗 2个疗程结束后3周行肿瘤细胞减灭术 ,术后继续化疗。B组 (6 2例 )首先减灭术 ,术后行腹腔化疗和静脉化疗。每组 6～ 8个疗程 ,药物为环磷酰胺、阿霉素和顺铂。结果 :A、B两组总 5年生存率分别为 2 5 .0 0 %和 43 .5 5 % (P <0 .0 5 )。减灭术理想的A、B组 5年生存率为 31.5 8%和 5 7.14% (P <0 .0 5 ) ;减灭术不理想的A、B组 5年生存率为 13.6 4%和 15 .0 0 % (P >0 .0 5 )。结论 :晚期卵巢癌合并腹水先手术后化疗比先化疗消除腹水后手术预后明显改善。更多还原

【Abstract】 Objective:To investigate the management of advanced epithelial ovarian cancer with ascites.Methods:Group A:Sixty cases of epithelial ovarian cancer were given intraperitoneal chemotherapy 2 or 3 times and intravenous chemotherapy for 2 courses then cytoreductive surgery was performed after three weeks.Group B:Sixty two cases of epithelial cancer underwent cytoreductive first,then intraperitoneal and intraveneous chemotherapy were given to them.The whole courses for the two groups were 6～8.The remedy was CAP(CTX,ADM,DDP).Results:The overall 5 year survival rate for the two groups was 25.00% and 43.55%,respectively.The difference was significant( P <0.05).The 5 year survival rate was 31.58% and 57.14%( P <0.05),for group A and B with optimal cytoreductive and it was 13.64% and 15.00%( P >0.05) for those without optimal cytoreductive.Conclusions:Surgery is suggested for advanced epithelial ovarian cancer with ascites before chemotherapy to achieve better prognosis.更多还原