【摘要】 目的：探讨艾滋病病毒相关性原发性脑淋巴瘤放射治疗的疗效。方法：从 １９９５年１月至 １９９９年 １２月法国巴黎第十二大学Ｈｅｎｒｉ Ｍｏｎｄｏｒ医院放疗科共收治艾滋病病毒相关性原发性脑淋巴瘤病人８例，均为男性，中位年龄为３２岁（２１～５７岁）。８例病人均接受全脑照射３０ Ｇｙ，后有４例缩野照射原发肿瘤 １５～２０ Ｇｙ，中位照射剂量为 ３７ ．５ Ｇｙ。所有病人均未接受化疗。结果：放疗结束时，肿瘤缩小４例，肿瘤无变化 ３例，肿瘤增大 １例；病人对急性放射反应耐受性尚好。病人中位生存期为７．１个月（３～１９个月）。结论：艾滋病病毒相关性原发性脑淋巴瘤病人的预后差，而放射治疗可在一定程度上延长病人的生存期。更多还原

【Abstract】 Objective: The retrospective analysis was conducted to study the effectiveness of radiotherapy for the patients with AIDS-related primary cerebral lymphoma. Methods: From January 1995 to December 1999, 8 patients with AIDS-related primary cerebral lymphoma were treated in Department Of Radiotherapy, Henri Mondor Hospital, Medical College, University Ⅻ of Paris. Median age was 32 years (range: 21 - 57 years). Eight patients received irradiation of 30 Gy to total brain, 4 patients continued to receive irradiation of 15 - 20 Gy to the primary cerebral tumor. The median dose of radiotherapy was 37. 5 Gy (30 - 50 Gy). ResultS: After radiotherapy, the tumor size in brain was reduced in 4 patients, did not change in 3 patients, and increased in I patient. The median survival was 7. 1 months (range: 3 - 19 months). Conclusions: There was poor survival for the patients with AIDS-related primary cerebral lymphoma and radiotherapy could prolong the survival of the patients.更多还原