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止呕合剂防治化疗诱发恶心呕吐反应的临床观察
Clinical Observation of Ziou Mixture in Treating Nausea and Vomiting Induced by Chemotherapy
【摘要】 目的:观察中药止呕合剂防治肿瘤化疗所致恶心呕吐反应的效果。方法:应用止呕合剂对88例患者进行治疗,同时设西药枢复宁为对照,对化疗药所致恶心呕吐反应的防治效果以及副作用进行临床研究。结果:中药组防治化疗所致呕吐显效率为84.7%,枢复宁组为66.6%(P<0.05);中药组总有效率为93.3%,枢复宁组为85.7%,两组比较无显著性差异。中药组副作用为6.5%.枢复宁组为54.7%,两组比较差异有非常显著性意义(P<0.01)。结论:该方具有防治肿瘤患者化疗所致呕吐反应的作用。
【Abstract】 Objective: To observe the effect of Ziou Mixture in treating nausea and vomiting induced by chemotherapy. Methods: 88 cases of malignant tumor with nausea and vomiting during chemotherapy were divided into Ziou group and the control group (treated with ondansetron). Results: the remarkedly effective rate in Ziou group and the control group was 84.7% and 66.6% respectively (P<0. 05); and the total effective rate was 93.3%, and 85. 7%, respectively, the difference being not significant. Side effect was obse rved in 6. 5% of Ziou group and 54. 7% of control group, the difference was significant (P<0. 01). Conclusion: Ziou Mixture can relieve nausea and vomiting induced by chemical therapy.
【Key words】 @Ziou Mixture/therapeutic use; Vomiting/therapy, TCM; Vomiting/chemically induced; Chemotherapy, adjuvant/adverse effects;
- 【文献出处】 中药新药与临床药理 ,Traditional Chinese Drug Research & Clinical Pharmacology , 编辑部邮箱 ,2000年03期
- 【分类号】R730.5
- 【被引频次】15
- 【下载频次】87