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止呕合剂防治化疗诱发恶心呕吐反应的临床观察

Clinical Observation of Ziou Mixture in Treating Nausea and Vomiting Induced by Chemotherapy

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【作者】 王德山单德红柴纪严巴淑芳李树林戴素华

【Author】 WANG De-shan, SHAN De-hong , CAI Ji-yan, et al. (Liaoning College of Traditional Chinese Medicine, Shenyang 110032)

【机构】 辽宁中医学院生理教研室辽宁省大洼县人民医院辽宁省大洼县人民医院 沈阳110032沈阳110032辽宁大洼114000辽宁大洼114000

【摘要】 目的:观察中药止呕合剂防治肿瘤化疗所致恶心呕吐反应的效果。方法:应用止呕合剂对88例患者进行治疗,同时设西药枢复宁为对照,对化疗药所致恶心呕吐反应的防治效果以及副作用进行临床研究。结果:中药组防治化疗所致呕吐显效率为84.7%,枢复宁组为66.6%(P<0.05);中药组总有效率为93.3%,枢复宁组为85.7%,两组比较无显著性差异。中药组副作用为6.5%.枢复宁组为54.7%,两组比较差异有非常显著性意义(P<0.01)。结论:该方具有防治肿瘤患者化疗所致呕吐反应的作用。

【Abstract】 Objective: To observe the effect of Ziou Mixture in treating nausea and vomiting induced by chemotherapy. Methods: 88 cases of malignant tumor with nausea and vomiting during chemotherapy were divided into Ziou group and the control group (treated with ondansetron). Results: the remarkedly effective rate in Ziou group and the control group was 84.7% and 66.6% respectively (P<0. 05); and the total effective rate was 93.3%, and 85. 7%, respectively, the difference being not significant. Side effect was obse rved in 6. 5% of Ziou group and 54. 7% of control group, the difference was significant (P<0. 01). Conclusion: Ziou Mixture can relieve nausea and vomiting induced by chemical therapy.

【基金】 辽宁省教育委员会资助项目(9807211060)
  • 【文献出处】 中药新药与临床药理 ,Traditional Chinese Drug Research & Clinical Pharmacology , 编辑部邮箱 ,2000年03期
  • 【分类号】R730.5
  • 【被引频次】15
  • 【下载频次】87
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